CuroNZ is a Biotechnology start-up company with a drug portfolio covering the peptide family, Neural Regeneration Peptides (NRPs), which were discovered by CuroNZ's founding Director, Dr Frank Sieg and first patented back in 2001.
Our plan for 2016 is to develop the drug candidate NRP2945 to end of IND to make it ready for clinical phase I development with the aim of licensing it or reaching other commercial arrangements to provide a clear pathway forward to bring this promising therapeutic treatment as quickly as possible to patients.
- Drug candidates: Neural Regeneration Peptides (NRPs) of synthetic origin, classified as NCEs
- Internationally granted patent claims for NRP2945 and other NRPs directed to neural regeneration and protection regarding the central nervous system
- In excess of NZ $10 million invested in the development of these class of compounds to date
- Lead compound NRP2945 in late phase of preclinical development (2. animal tox) including CMC package finalization
- Unique mechanism of action which produces both regeneration of CNS tissue and anti-inflammatory effects
- Support from the General US-based Fast Forward fund (MS society), from the New Zealand government and private equity investment up to IND
- Late in 2017 NRP2945 will be trialled for refractory epilepsy in children diagnosed with Lennox-Gastaut Syndrome (LGS)
- Potential for Orphan drug designation and breakthrough status for NRPs
These exciting peptides have proven efficacy within various neurodegenerative animal disease models indicating significant future therapeutic effects for several human central neural system diseases which currently have few or no treatments and potentially other applications.
Our drug candidate has huge potential, however, we need a pharma partner or clinical phase investment to enable us to achieve our technical and commercial goals.